The effects of gender on electrical therapies for the heart: procedural considerations, results and complications: A report from the XII Congress of the Italian Association on Arrhythmology and Cardiostimulation (AIAC). in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology / Europace. 2017 Dec 1;19(12):1911-1921. doi: 10.1093/europace/eux034.
2017
AOU Città della Salute di Torino
Tipo pubblicazione
Review
Autori/Collaboratori (14)Vedi tutti...
Diemberger I
Institute of Cardiology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Policlinico S.Orsola-Malpighi, Via Massarenti n. 9, 40138, Bologna, Italy.
Marazzi R
Department of Heart and Vessels, Ospedale di Circolo e Fondazione Macchi, University of Insubria, Varese, Italy.
Casella M
Cardiac Arrhythmia Research Center, Centro Cardiologico Monzino IRCCS, Milan, Italy.
et alii...
Abstract
Use of cardiac implantable devices and catheter ablation is steadily increasing in Western countries following the positive results of clinical trials. Despite the advances in scientific knowledge, tools development, and techniques improvement we still have some grey area in the field of electrical therapies for the heart. In particular, several reports highlighted differences both in medical behaviour and procedural outcomes between female and male candidates. Women are referred later for catheter ablation of supraventricular arrhythmias, especially atrial fibrillation, leading to suboptimal results. On the opposite females present greater response to cardiac resynchronization, while the benefit of implantable defibrillator in primary prevention seems to be less pronounced. Differences on aetiology, clinical profile, and development of myocardial scarring are the more plausible causes. This review will discuss all these aspects together with gender-related differences in terms of acute/late complications. We will also provide useful hints on plausible mechanisms and practical procedural aspects.
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PMID : 28520959
DOI : 10.1093/europace/eux034
Keywords
Aged; Arrhythmias, Cardiac/diagnosis/mortality/physiopathology/therapy; Cardiac Resynchronization Therapy/adverse effects/mortality; Cardiac Resynchronization Therapy Devices; Catheter Ablation/adverse effects/mortality; Congresses as Topic; Defibrillators, Implantable; Electric Countershock/adverse effects/instrumentation/mortality; Female; Health Status Disparities; Healthcare Disparities; Humans; Male; Middle Aged; Process Assessment, Health Care; Risk Factors; Sex Factors; Treatment Outcome; Ablation; Arrhythmia; CIED; Defibrillator; Gender; Review; Sex;