Impact of gender on immature platelet count and its relationship with coronary artery disease. in Journal of thrombosis and thrombolysis / J Thromb Thrombolysis. 2020 May;49(4):511-521. doi: 10.1007/s11239-020-02080-0.
2020
AOU Novara
Tipo pubblicazione
Journal Article
Autori/Collaboratori (6)Vedi tutti...
Negro F
Department of Translational Medicine, Ospedale "Maggiore Della Carità", Eastern Piedmont University, C.so Mazzini, 18, 28100, Novara, Italy.
Verdoia M
Department of Translational Medicine, Ospedale "Maggiore Della Carità", Eastern Piedmont University, C.so Mazzini, 18, 28100, Novara, Italy.
Tonon F
Ospedale Degli Infermi, ASL Biella, Biella, Italy.
et alii...
Abstract
The impact of platelet parameters on the cardiovascular risk is still debated. Gender differences in platelet volume indexes and turnover have been previously reported, potentially conditioning their role in the development of coronary artery disease (CAD). However, few studies have addressed, so far, the impact of gender on the immature platelet fraction (IPF) and count (IPC) and their relationship with CAD. We enrolled consecutive patients undergoing coronary angiography in a single centre. IPF and platelet indexes were measured at admission. Significant CAD was defined as the presence of at least one coronary stenosis more than 50%. A total of 2550 patients were included, 1835 (72%) were males, and 715 (28%) were females. Female patients were older (p?
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PMID : 32189190
DOI : 10.1007/s11239-020-02080-0
Keywords
Aged; Aged, 80 and over; Blood Platelets; Coronary Artery Disease/blood; Female; Humans; Italy/epidemiology; Male; Middle Aged; Platelet Count; Prevalence; Prospective Studies; Sex Factors; Coronary artery disease; Gender; Immature platelet fraction; Reticulated platelets;