Gender differences in percutaneous coronary intervention for chronic total occlusions from the ERCTO study. in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions / Catheter Cardiovasc Interv. 2023 Apr;101(5):918-931. doi: 10.1002/ccd.30616. Epub 2023 Mar 8.
2023
ASL Città di Torino
Tipo pubblicazione
Journal Article
Autori/Collaboratori (36)Vedi tutti...
Avran A
Centre Hospitalier de Valenciennes, Valenciennes, France.
Zuffi A
Cardiology Unit, Saint Martin Private Hospital Center, Caen, France.
Gobbi C
Cardiology Unit, Saint Martin Private Hospital Center, Caen, France.
et alii...
Abstract
BACKGROUND: Gender-specific data addressing percutaneous coronary intervention (PCI) of chronic total occlusion (CTO) in female patients are scarce and based on small sample size studies. AIMS: We aimed to analyze gender-differences regarding in-hospital clinical outcomes after CTO-PCI. METHODS: Data from 35,449 patients enrolled in the prospective European Registry of CTOs were analyzed. The primary outcome was the comparison of procedural success rate in the two cohorts (women vs. men), defined as a final residual stenosis less than 20%, with Thrombolysis In Myocardial Infarction grade flow?=?3. In-hospital major adverse cardiac and cerebrovascular events (MACCEs) and procedural complications were deemed secondary outcomes. RESULTS: Women represented 15.2% of the entire study population. They were older and more likely to have hypertension, diabetes, and renal failure, with an overall lower J-CTO score. Women showed a higher procedural success rate (adjusted OR [aOR]?=?1.115, confidence interval [CI]: 1.011-1.230, p?=?0.030). Apart from previous myocardial infarction and surgical revascularization, no other significant gender differences were found among predictors of procedural success. Antegrade approach with true-to-true lumen techniques was more commonly used than retrograde approach in females. No gender differences were found regarding in-hospital MACCEs (0.9% vs. 0.9%, p?=?0.766), although a higher rate of procedural complications was observed in women, such as coronary perforation (3.7% vs. 2.9%, p?
Accesso banca dati bibliografica
Accedi alla scheda bibliografica del documento in PUBMED
PMID : 36883958
DOI : 10.1002/ccd.30616
Keywords
Registries; Myocardial Infarction/etiology; Treatment Outcome; Risk Factors; Prospective Studies; Coronary Occlusion/diagnostic imaging/therapy/complications; Percutaneous Coronary Intervention/adverse effects/methods; Female; Humans; Male; percutaneous coronary intervention; major adverse cardiac and cerebrovascular events; gender differences; female sex; chronic total occlusion; Coronary Angiography/adverse effects; Chronic Disease;